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KMID : 1036520140040020037
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Clinical Neuro-Ophthalmology
2014 Volume.4 No. 2 p.37 ~ p.43
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Ischemic Optic Neuropathy
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Park Ji-Yun
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Abstract
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Ischemic optic neuropathy may be classified into two types: anterior ischemic optic neuropathy (AION) presenting pale edema of the optic disc and posterior ischemic optic neuropathy (PION) manifesting no remarkable changes on the optic disc during the acute stage. AION results from ischemic damage to the anterior portion of the optic nerve, which is primarily supplied by the posterior ciliary artery circulation. AION is generally divided into two types: arteritic AION (AAION), resulting from ischemia secondary to vasculitis (usually from giant cell arteritis, GCA), and non arteritic AION (NAION), resulting from noninflammatory small-vessel infarction of anterior optic nerve. PION is much less common than AION and also is divided into arteritic and nonarteritic conditions. PION generally occurs in either the perioperative setting or in the setting of GCA or other vasculitides and should be differentiated from any retrobular optic nerve pathology including compressive, inflammatory, and infiltrative optic neuropathies. While the management of arteritic ischemic optic neuropathy is relatively straight forward with steroids, various therapeutic trials for nonarteritic type has been applied but not established yet.
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KEYWORD
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ISchemic optic neuropathy, Optic nerve disease, Giant cell arteritis
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